Dichlorobenzyl chloride → HCID 68184280, 화합물

HRID 878997

반응식

HRID 878997 반응식
[Br:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([CH3:11])=[N:7][NH:8]2)=[CH:4][CH:3]=1.[Cl:12][C:13]1[C:20]([Cl:21])=[CH:19][CH:18]=[CH:17][C:14]=1[CH2:15]Cl.C(N1C2C(=CC=C(C(O)=O)C=2)C=C1)C1C=CC=CC=1>>[Br:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([CH3:11])=[N:7][N:8]2[CH2:15][C:14]2[CH:17]=[CH:18][CH:19]=[C:20]([Cl:21])[C:13]=2[Cl:12])=[CH:4][CH:3]=1

참가 물질

4

반응물 3

HCID 76790Dichlorobenzyl chlorideHCID 179478751-Benzyl-1H-indole-6-carboxylic acidHCID 178434209HCID 178434209, 화합물

생성물 1

HCID 68184280HCID 68184280, 화합물수율 85.5%

실험 절차

The titled compound (228 mg) as a white solid was prepared from the 6-bromo-3-methyl-1H-indazole (152 mg) obtained with the method described in the document (JP 2009-528363 W) and 2,3-dichlorobenzyl chloride (215 mg) according to the method of the process (1) of Example 66.

후처리

  1. customobtained with the method

출처 및 근거

ORD 기록
ord-3197af0bf3864058b1276d64180ca859
출처 데이터셋
uspto-grants-2015_03
특허 번호
US08987473B2

연결된 노트

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