HCID 86700409, 화합물 → HCID 86700408, 화합물

HRID 879594노트

반응식

HRID 879594 반응식
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][C:7]([CH:11]3[CH2:16][NH:15][C:14](=O)[CH2:13][O:12]3)=[CH:8][CH:9]=2)[CH:4]=[N:3]1>C1COCC1>[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][C:7]([CH:11]3[O:12][CH2:13][CH2:14][NH:15][CH2:16]3)=[CH:8][CH:9]=2)[CH:4]=[N:3]1

참가 물질

3

반응물 1

HCID 86700409HCID 86700409, 화합물

생성물 1

HCID 86700408HCID 86700408, 화합물

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매2회

실험 절차

To a solution of 6-(1-methyl-1H-indazol-5-yl)morpholin-3-one (17.8 mg, 0.077 mmol) in THF was added BH3 in THF (1M, mmol). The resulting mixture was stirred at room temperature for 10 hr. The crude compound was evaporated to dryness and used for the next step without further purification. LCMS-ESI+: calc'd for C12H15N3O: 218.1 (M+H+); found: 218.2 (M+H+).

후처리

  1. customThe crude compound was evaporated to dryness
  2. customused for the next step without further purification

출처 및 근거

ORD 기록
ord-af3458411c5147519def525373ce9cb5
출처 데이터셋
uspto-grants-2015_03
특허 번호
US08987250B2

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