HCID 66730327, 화합물 → HCID 66730359, 화합물

HRID 880740노트

반응식

HRID 880740 반응식
[CH3:1][O:2][C:3]([CH:5]1[CH2:10][CH:9]([O:11][C:12]2[C:21]3[C:16](=[C:17]([CH3:24])[C:18]([O:22][CH3:23])=[CH:19][CH:20]=3)[N:15]=[C:14]([C:25]3[S:26][CH:27]=[C:28]([C:30]([F:33])([F:32])[F:31])[N:29]=3)[N:13]=2)[CH2:8][CH2:7][N:6]1C)=[O:4].COC(C1CC(OC2C3C(=C(C)C(OC)=CC=3)N=C(C3SC=C(C(F)(F)F)N=3)C=2)CCN1)=O>>[CH3:1][O:2][C:3]([CH:5]1[CH2:10][CH:9]([O:11][C:12]2[C:21]3[C:16](=[C:17]([CH3:24])[C:18]([O:22][CH3:23])=[CH:19][CH:20]=3)[N:15]=[C:14]([C:25]3[S:26][CH:27]=[C:28]([C:30]([F:31])([F:32])[F:33])[N:29]=3)[N:13]=2)[CH2:8][CH2:7][NH:6]1)=[O:4]

참가 물질

3

반응물 2

HCID 66730327HCID 66730327, 화합물HCID 667303534-[7-Methoxy-8-methyl-2-(4-trifluoromethyl-thiazol-2-yl)-quinolin-4-yloxy]-piperidine-2-carboxylic acid methyl ester

생성물 1

HCID 66730359HCID 66730359, 화합물수율 55%

실험 절차

Compound 23 was synthesized from compound 22 as a pale yellow powder in 55% yield according to the procedure as described for compound 14. MS (ESI, EI+) m/z=483 (MH+).

출처 및 근거

ORD 기록
ord-e0fc66da42e54ce6b1c8903cd42f03df
출처 데이터셋
uspto-grants-2015_03
특허 번호
US08993595B2

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