7-(trifluoromethyl)-1H-indazole-5-carboxylic acid → HCID 178524179, 화합물

반응식

FC(F)(F)[C:3]1[CH:4]=[C:5]([C:12]([OH:14])=[O:13])[CH:6]=[C:7]2[C:11]=1[NH:10][N:9]=[CH:8]2.BrC1C=C2C(=CC=1)NN=C2[C:27]([F:30])([F:29])[F:28]>>[F:28][C:27]([F:30])([F:29])[C:8]1[C:7]2[C:11](=[CH:3][CH:4]=[C:5]([C:12]([OH:14])=[O:13])[CH:6]=2)[NH:10][N:9]=1

참가 물질

반응물 2

HCID 674918107-(trifluoromethyl)-1H-indazole-5-carboxylic acid

HCID 178506287HCID 178506287, 화합물

생성물 1

HCID 178524179HCID 178524179, 화합물

실험 절차

The title compound was prepared by a method analogous to that described in Steps 3-4 of Intermediate 21, using 5-bromo-3-(trifluoromethyl)-1H-indazole. +ESI (M+H) 231.1.

출처 및 근거

ORD 기록: ord-c4db7fe3ad4e437c9e4a4077c29006a7
출처 데이터셋: uspto-grants-2015_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08993586B2

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