Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetonitrile → 4-Amino-4'-propylazobenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetonitrile | HCID 6342 | — |
| 반응물 | Benzenamine, 2-(2-phenyldiazenyl)- | HCID 76077 | — |
| 반응물 | Diisopropylethylamine | HCID 81531 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 4-Amino-4'-propylazobenzene | HCID 23513408 | — |
반응 단계
To a solution of the aminoazobenzene (1 eq) and DIPEA (2 eq) in 1:1 MeCN:DMF at 0° C. was added 2-triethylammonium acetic acid chloride chloride8 (1.5 eq) in 1:1 MeCN:DMF and stirred for 15 min, then warmed to ambient temperature and stirred for 1-12 h at which time the solvent was removed in vacuo for purification by reverse phase silica gel chromatography (0.1% formic acid in H2O, gradient up to 50% MeCN: 0.1% formic acid in H2O).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08993736B2 |
| 출처 데이터셋 | uspto-grants-2015_03 |
| ORD ID | ord-6485a541c44e4403a60b8eb8b2530f9f |
| 출처 메모 | uspto-grants-2015_03 |