3-Hydroxybenzaldehyde → 3-(2-Hydroxy-2-phenylethoxy)benzaldehyde

HRID 882481

반응식

HRID 882481 반응식
[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH:5]=[O:6].[CH2:10]1[O:18][CH:11]1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[OH:18][CH:11]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH2:10][O:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH:5]=[O:6]

참가 물질

3

반응물 2

HCID 1013-HydroxybenzaldehydeHCID 7276Styrene Oxide

생성물 1

HCID 607085333-(2-Hydroxy-2-phenylethoxy)benzaldehyde

실험 절차

Alkylation reaction of 3-hydroxybenzaldehyde with styrene oxide gave 3-(2-hydroxy-2-phenylethoxy)benzaldehyde as a clear oil. Yield (0.9 g, 48%): 1H NMR (400 MHz, CDCl3) δ 9.89 (s, 1H), 7.23-7.41 (m, 8H), 7.16 (d, J=8.0 Hz, 1H), 5.35 (dd, J=8.2, 3.4 Hz, 1H), 3.93-4.0 (m, 1H), 3.82-3.89 m, 1H).

출처 및 근거

ORD 기록
ord-d812eb480863498eab7462bd741a6eb6
출처 데이터셋
uspto-grants-2015_03
특허 번호
US08993807B2

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