Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Rosiglitazone → Pioglitazone, (R)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Rosiglitazone | HCID 77999 | — |
| 반응물 | (E)-5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione | HCID 14211277 | — |
| 생성물 | Pioglitazone, (R)- | HCID 29010894 | — |
반응 단계
Biocatalytic reduction of 5-[1-{4-[2-(5-ethyl-pyridin-2-yl)-ethoxy]-phenyl}-meth-(E)-ylidene]-thiazolidine-2,4-dione was investigated using literature procedures described for Rosiglitazone (J. Chem. Soc. Perkin Trans. I, 1994, 3319-3324).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08236786B2 |
| 출처 데이터셋 | uspto-grants-2012_08 |
| ORD ID | ord-a1d64ffa47914ff0add7c2fa22c7cfca |
| 출처 메모 | uspto-grants-2012_08 |