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[C:1](/[C:3](=[C:8]1/[C:9](=[O:22])[NH:10][C:11]2[C:16]/1=[CH:15][C:14]([O:17][C:18]([F:21])([F:20])[F:19])=[CH:13][CH:12]=2)/[C:4]([O:6][CH3:7])=[O:5])#[N:2].[C-:23]#[N:24].[K+]>>[C:1]([CH:3]([C:8]1([C:23]#[N:24])[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([O:17][C:18]([F:19])([F:21])[F:20])[CH:15]=2)[NH:10][C:9]1=[O:22])[C:4]([O:6][CH3:7])=[O:5])#[N:2]참가 물질
3
실험 절차
Following the general method as outlined for Intermediate 5, starting from methyl (2Z)-cyano[2-oxo-5-(trifluoromethoxy)-1,2-dihydro-3H-indol-3-ylidene]acetate (intermediate 3) and potassium cyanide, the title compound was isolated, after evaporation, as a pale brown solid in 90% yield. This was a mixture of diastereomers.
출처 및 근거
- ORD 기록
- ord-f3d4a8b30f0a4d6894bd12c0f1f01b3b
- 출처 데이터셋
- uspto-grants-2012_08
- 특허 번호
- US08236963B2
연결된 노트
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