Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Cyanide → methyl cyano[3-cyano-2-oxo-5-(trifluoromethoxy)-2,3-dihydro-1H-indol-3-yl]acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Cyanide | HCID 9032 | — |
| 반응물 | methyl (2Z)-cyano[2-oxo-5-(trifluoromethoxy)-1,2-dihydro-3H-indol-3-ylidene]acetate | HCID 67424559 | — |
| 생성물 | methyl cyano[3-cyano-2-oxo-5-(trifluoromethoxy)-2,3-dihydro-1H-indol-3-yl]acetate | HCID 67425381 | 90% |
반응 단계
Following the general method as outlined for Intermediate 5, starting from methyl (2Z)-cyano[2-oxo-5-(trifluoromethoxy)-1,2-dihydro-3H-indol-3-ylidene]acetate (intermediate 3) and potassium cyanide, the title compound was isolated, after evaporation, as a pale brown solid in 90% yield. This was a mixture of diastereomers.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08236963B2 |
| 출처 데이터셋 | uspto-grants-2012_08 |
| ORD ID | ord-f3d4a8b30f0a4d6894bd12c0f1f01b3b |
| 출처 메모 | uspto-grants-2012_08 |