Diethyl 2-((6-ethylpyridin-2-ylamino)methylene)malonate → Ethyl 7-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
반응식
C(O[C:4](=[O:21])[C:5](=[CH:11][NH:12][C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([CH2:19][CH3:20])[N:14]=1)[C:6]([O:8][CH2:9][CH3:10])=[O:7])C>C1(OC2C=CC=CC=2)C=CC=CC=1>[CH2:9]([O:8][C:6]([C:5]1[C:4](=[O:21])[C:18]2[C:13](=[N:14][C:15]([CH2:19][CH3:20])=[CH:16][CH:17]=2)[NH:12][CH:11]=1)=[O:7])[CH3:10]참가 물질
3
실험 절차
The product of Example 8c (7.16 g, 0.024 mol) was heated in diphenyl ether following the procedure in Example 7b giving the title compound (4.73 g, 79%) as a tan solid.
출처 및 근거
- ORD 기록
- ord-ff726582d819408680e736186e326802
- 출처 데이터셋
- uspto-grants-2012_08
- 특허 번호
- US08236950B2
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