참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Cesium carbonate | HCID 10796 | — |
| 반응물 | 4-Chloro-3-nitrophenol | HCID 69127 | — |
| 반응물 | 4'-Mercaptoacetanilide | HCID 70777 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | N-[4-(4-Hydroxy-2-nitro-phenylsulfanyl)-phenyl]-acetamide | HCID 67249335 | 100% |
반응 단계
A mixture of 3-nitro-4-chloro phenol (1.59 g, 8.97 mmol), 4-acetamidothiophenol (2 g, 10.76 mmol) and cesium carbonate (7.0 g, 21.53 mmol) in DMF (20 mL) was heated 2.5 h at 100° C. The mixture was cooled, poured onto ice and the resulting solid is collected by filtration and dried under vacuum the title compound leaving a yellow solid (2.7 g, 100%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08236950B2 |
|---|
| 출처 데이터셋 | uspto-grants-2012_08 |
|---|
| ORD ID | ord-911e024ca10e470ab9d11f43a6db3809 |
|---|
| 출처 메모 | uspto-grants-2012_08 |
|---|
