Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(S)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-3-((S)-piperidin-3-yl)-1,3-oxazinan-2-one → (S)-3-((S)-1-(5-chloro-6-methylpyridazin-3-yl)piperidin-3-yl)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-1,3-oxazinan-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (S)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-3-((S)-piperidin-3-yl)-1,3-oxazinan-2-one | HCID 58278645 | — |
| 반응물 | 4,6-Dichloro-3-methylpyridazine | HCID 58717049 | — |
| 생성물 | (S)-3-((S)-1-(5-chloro-6-methylpyridazin-3-yl)piperidin-3-yl)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-1,3-oxazinan-2-one | HCID 58278656 | — |
반응 단계
The title compound was prepared from (S)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-3-((S)-piperidin-3-yl)-1,3-oxazinan-2-one and 4,6-dichloro-3-methylpyridazine following a procedure analogous to that described in Example 1. LC-MS Method 1 tR=1.37 min, m/z=459, 461(M+1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08242111B2 |
| 출처 데이터셋 | uspto-grants-2012_08 |
| ORD ID | ord-7a8639f7f84644d7859d067413fed446 |
| 출처 메모 | uspto-grants-2012_08 |