Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosphorus tribromide → [3-(4-Bromo-2-bromomethyl-phenoxy)-phenyl]-acetic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosphorus tribromide | HCID 24614 | — |
| 반응물 | [3-(4-Bromo-2-hydroxymethyl-phenoxy)-phenyl]-acetic acid ethyl ester | HCID 58237503 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | [3-(4-Bromo-2-bromomethyl-phenoxy)-phenyl]-acetic acid ethyl ester | HCID 58237602 | 75.3% |
반응 단계
To [3-(4-bromo-2-hydroxymethyl-phenoxy)-phenyl]-acetic acid ethyl ester (0.7 g, 1.86 mmol) in 1,4-dioxane (10 mL) was added phosphorus tribromide (0.19 mL, 2.04 mmol), and the reaction was stirred for 1 hour at room temperature. After work-up, 0.6 g of the desired product was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08242145B2 |
| 출처 데이터셋 | uspto-grants-2012_08 |
| ORD ID | ord-21b7adda40d34c2cbf5f59cf3b4a9824 |
| 출처 메모 | uspto-grants-2012_08 |