HCID 57420172, 화합물 → HCID 57420174, 화합물

HRID 887063노트

반응식

HRID 887063 반응식
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[N:9]1[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][CH2:17][C:18]([O:20][C:21]2[CH:30]=[C:29]3[C:24]([CH2:25][CH2:26][C:27](=[O:31])[NH:28]3)=[CH:23][CH:22]=2)=[O:19])[CH2:11][CH2:10]1.Cl.COC1C=CC=CC=1N1CCN(CCCC(OC2C=C3C(CCC(=O)N3)=CC=2)=O)CC1>>[ClH:1].[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[N:9]1[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][CH2:17][C:18]([O:20][C:21]2[CH:30]=[C:29]3[C:24]([CH2:25][CH2:26][C:27](=[O:31])[NH:28]3)=[CH:23][CH:22]=2)=[O:19])[CH2:13][CH2:14]1

참가 물질

3

반응물 2

HCID 57420172HCID 57420172, 화합물HCID 57420173HCID 57420173, 화합물

생성물 1

HCID 57420174HCID 57420174, 화합물

실험 절차

2-Oxo-1,2,3,4-tetrahydroquinolin-7-yl 4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butanoate hydrochloride (20b) (Scheme 3) was prepared from the compound 19b according to the protocol described for the compound 20a (Example 29). The hydrochloride salt 20b gave satisfactory 1H NMR spectral data. White solid, 0.11 g (98%). MS (ESI): m/z=462.1 (M+).

출처 및 근거

ORD 기록
ord-90ede9d1dad9465aac6f9404582fbb49
출처 데이터셋
uspto-grants-2012_08
특허 번호
US08247420B2

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