Benzene, (2-bromoethoxy)- → 2-Methyl-4-[2-methyl-1-(2-phenoxy-ethyl)-1H-imidazol-4-ylethynyl]-pyridine

반응식

[CH3:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:4][N:3]=1.[O:16]([CH2:23][CH2:24]Br)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH3:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[N:13]([CH2:24][CH2:23][O:16][C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH:14]=2)[CH:5]=[CH:4][N:3]=1

참가 물질

반응물 2

HCID 68526Benzene, (2-bromoethoxy)-

HCID 178418884HCID 178418884, 화합물

생성물 1

HCID 692908232-Methyl-4-[2-methyl-1-(2-phenoxy-ethyl)-1H-imidazol-4-ylethynyl]-pyridine

실험 절차

The title compound, MS: m/e=318.1 (M+H+), was prepared in accordance with the general method of example 1 from 2-methyl-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 2-phenoxyethyl bromide.

출처 및 근거

ORD 기록: ord-a6532b9a829e4ccda2f3f44872e35bdb
출처 데이터셋: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07091222B2

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