1-Methyl-4-(5-nitro-2-pentafluoroethyl-benzyl)-piperazine → 3-(4-Methyl-piperazin-1-ylmethyl)-4-pentafluoroethyl-phenylamine

HRID 888108노트

반응식

HRID 888108 반응식
[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([CH2:8][C:9]2[CH:14]=[C:13]([N+:15]([O-])=O)[CH:12]=[CH:11][C:10]=2[C:18]([F:24])([F:23])[C:19]([F:22])([F:21])[F:20])[CH2:4][CH2:3]1.FC(F)(C1C=CC(N)=CC=1OCCN1CCCC1)C(F)(F)F>>[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([CH2:8][C:9]2[CH:14]=[C:13]([NH2:15])[CH:12]=[CH:11][C:10]=2[C:18]([F:24])([F:23])[C:19]([F:20])([F:21])[F:22])[CH2:4][CH2:3]1

참가 물질

3

반응물 2

HCID 222492671-Methyl-4-(5-nitro-2-pentafluoroethyl-benzyl)-piperazineHCID 860022324-Pentafluoroethyl-3-(2-pyrrolidin-1-yl-ethoxy)-phenylamine

생성물 1

HCID 219594843-(4-Methyl-piperazin-1-ylmethyl)-4-pentafluoroethyl-phenylamine

실험 절차

3-(4-Methyl-piperazin-1-ylmethyl)-4-pentafluoroethyl-phenylamine was prepared from 1-Methyl-4-(5-nitro-2-pentafluoroethyl-benzyl)-piperazine similar to that described in the preparation of 4-Pentafluoroethyl-3-(2-pyrrolidin-1-yl-ethoxy)-phenylamine.

출처 및 근거

ORD 기록
ord-3a1cb6213d214f1f81167bac14ea3d3f
출처 데이터셋
uspto-grants-2012_08
특허 번호
US08247556B2

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