Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Bromo-2,3-dihydro-1-benzofuran → (3R)-1-(2,3-dihydro-1-benzofuran-5-yl)-3-methylpiperazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Bromo-2,3-dihydro-1-benzofuran | HCID 2776159 | — |
| 반응물 | (3R)-1-(3,4-dimethoxyphenyl)-3-methylpiperazine | HCID 58487959 | — |
| 생성물 | (3R)-1-(2,3-dihydro-1-benzofuran-5-yl)-3-methylpiperazine | HCID 11651447 | — |
반응 단계
The title compound was prepared following the procedure of Intermediate 25, but starting from 5-bromo-2,3-dihydrobenzo[b]furan. Purification by flash chromatography (CHCl3/MeOH) gave the title compound as a brown oil. M+(ESI): 219.2. HPLC (Condition A), Rt: 1.3 min (HPLC purity: 99.9%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08247437B2 |
| 출처 데이터셋 | uspto-grants-2012_08 |
| ORD ID | ord-c5f72056f07d470da389ea08d9d675b5 |
| 출처 메모 | uspto-grants-2012_08 |