3-Isopropenyl-5-(5-methylpyridin-2-yl)benzoic acid → 3-Isopropyl-5-(5-methylpyridin-2-yl)benzoic acid
반응식
[C:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([C:13]2[CH:18]=[CH:17][C:16]([CH3:19])=[CH:15][N:14]=2)[CH:12]=1)[C:7]([OH:9])=[O:8])([CH3:3])=[CH2:2].[H][H]>C(O)C.[Pd]>[CH:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([C:13]2[CH:18]=[CH:17][C:16]([CH3:19])=[CH:15][N:14]=2)[CH:12]=1)[C:7]([OH:9])=[O:8])([CH3:3])[CH3:2]참가 물질
5
실험 절차
To a solution of 3-isopropenyl-5-(5-methylpyridin-2-yl)benzoic acid (150 mg, 0.592 mmol) in ethanol (11.8 mL) was added 10% palladium on carbon (50.0 mg, 0.047 mmol) and the mixture was placed under 1 atm of hydrogen. After 1 h, filtration and concentration gave the crude title compound (150 mg). MS 256.2 (M+1).
후처리
- filtrationfiltration and concentration
출처 및 근거
- ORD 기록
- ord-e39aa2da1d1246808d1f71cb8338f589
- 출처 데이터셋
- uspto-grants-2012_08
- 특허 번호
- US08247401B2
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