3-(4-Aminophenyl)-1,4-dimethylpiperazin-2-one → (R)-5-bromo-3-(4-(1,4-dimethyl-3-oxopiperazin-2-yl)phenylamino)-1-methylpyrazin-2(1H)-one

참여 물질

역할	이름	HCID	투입량
반응물	3-(4-Aminophenyl)-1,4-dimethylpiperazin-2-one	HCID 57625120	—
반응물	5-Bromo-3-(4-(1,4-dimethyl-3-oxopiperazin-2-yl)phenylamino)-1-methylpyrazin-2(1H)-one	HCID 57625129	—
생성물	(R)-5-bromo-3-(4-(1,4-dimethyl-3-oxopiperazin-2-yl)phenylamino)-1-methylpyrazin-2(1H)-one	HCID 57625140	—

The (R)-isomer of compound 14 can be prepared from the (+)-isomer of 1,4-dimethyl-3-(4-aminophenyl)piperazin-2-one using the same procedure.