Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide → 4-Methyl-1-(4-(trifluoromethyl)phenyl)pentan-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide | HCID 14069348 | — |
| 반응물 | HCID 178418529 | HCID 178418529 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 4-Methyl-1-(4-(trifluoromethyl)phenyl)pentan-1-one | HCID 46941396 | 77% |
반응 단계
With the similar conditions of Example 29, steps (a) and (c), reaction of N-Methoxy-N-methyl-4-trifluoromethyl-benzamide, compound 31 a, with 3-methyl-1-butyl magnesium bromide, compound 29a, in THF gave the title compound in 77% yield; Calcd MW 244.26. Found MH+ 245.2.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08247610B2 |
| 출처 데이터셋 | uspto-grants-2012_08 |
| ORD ID | ord-42b29be0db1342bfaf79a46419c91ce7 |
| 출처 메모 | uspto-grants-2012_08 |