2-Chloro-4-iodopyridine → 2-Chloro-4-(1-cyclopropyl-2,5-dimethyl-1H-imidazol-4-ylethynyl)-pyridine

HRID 8887노트

반응식

HRID 8887 반응식
[CH:1]1([N:4]2[C:8]([CH3:9])=[C:7]([C:10]#[CH:11])[N:6]=[C:5]2[CH3:12])[CH2:3][CH2:2]1.[Cl:13][C:14]1[CH:19]=[C:18](I)[CH:17]=[CH:16][N:15]=1>>[Cl:13][C:14]1[CH:19]=[C:18]([C:11]#[C:10][C:7]2[N:6]=[C:5]([CH3:12])[N:4]([CH:1]3[CH2:3][CH2:2]3)[C:8]=2[CH3:9])[CH:17]=[CH:16][N:15]=1

참가 물질

3

반응물 2

HCID 15165112-Chloro-4-iodopyridineHCID 219853851-cyclopropyl-4-ethynyl-2,5-dimethyl-1H-imidazole

생성물 1

HCID 865958972-Chloro-4-(1-cyclopropyl-2,5-dimethyl-1H-imidazol-4-ylethynyl)-pyridine

실험 절차

The title compound, MS: m/e=272.0 (M+H+), was prepared in accordance with the general method of example A, step 1 from 1-cyclopropyl-4-ethynyl-2,5-dimethyl-1H-imidazole and 2-chloro-4-iodo-pyridine.

출처 및 근거

ORD 기록
ord-f135c788388643a69501e1ab66510513
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07091222B2

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