2-Methylbenzoyl chloride → 2-Cyclooctyl-4,4-dimethyl-1-[(2-methylphenyl)carbonyl]-1,2-diazetidin-3-one

반응식

[CH:1]1([N:9]2[C:12](=[O:13])[C:11]([CH3:15])([CH3:14])[NH:10]2)[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:16][C:17]1[CH:25]=[CH:24][CH:23]=[CH:22][C:18]=1[C:19](Cl)=[O:20]>>[CH:1]1([N:9]2[C:12](=[O:13])[C:11]([CH3:15])([CH3:14])[N:10]2[C:19]([C:18]2[CH:22]=[CH:23][CH:24]=[CH:25][C:17]=2[CH3:16])=[O:20])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

참가 물질

반응물 2

HCID 702762-Methylbenzoyl chloride

HCID 673029832-Cyclooctyl-4,4-dimethyl-1,2-diazetidin-3-one

생성물 1

HCID 593614062-Cyclooctyl-4,4-dimethyl-1-[(2-methylphenyl)carbonyl]-1,2-diazetidin-3-one

실험 절차

2-Cyclooctyl-4,4-dimethyl-1,2-diazetidin-3-one and 2-methylbenzoyl chloride were used for a similar reaction and treatment as Example 96, and the title compound was obtained as a white crystalline powder.

출처 및 근거

ORD 기록: ord-64524f5530c2436fad19e8ff36ca96f5
출처 데이터셋: uspto-grants-2012_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08252781B2

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