1-Bromo-5-fluoro-2-methyl-3-nitrobenzene → 4-Bromo-6-fluoro-1H-indole

HRID 888903

반응식

HRID 888903 반응식
CN(C)S([C:6]1[CH:14]=[C:13]2[C:9]([CH:10]=[CH:11][NH:12]2)=[C:8]([Br:15])[CH:7]=1)(=O)=O.BrC1C=C([F:24])C=C([N+]([O-])=O)C=1C>>[Br:15][C:8]1[CH:7]=[C:6]([F:24])[CH:14]=[C:13]2[C:9]=1[CH:10]=[CH:11][NH:12]2

참가 물질

3

반응물 2

HCID 27733851-Bromo-5-fluoro-2-methyl-3-nitrobenzeneHCID 591513424-bromo-1H-indole-6-sulfonic acid dimethylamide

생성물 1

HCID 247281734-Bromo-6-fluoro-1H-indole

실험 절차

Prepared according to the method used in the preparation of 4-bromo-1H-indole-6-sulfonic acid dimethylamide using 1-bromo-5-fluoro-2-methyl-3-nitro-benzene in place of 3-bromo-4-N,N-trimethyl-5-nitro-benzenesulfonamide. The title compound was obtained as a white solid (6.06 g, 33%).

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-39a1186c9dde4a19b56ccaa3fe1d81a5
출처 데이터셋
uspto-grants-2012_08
특허 번호
US08252792B2

연결된 노트

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