Ethyl chloroformate → HCID 68675322, 화합물

HRID 889161노트

반응식

HRID 889161 반응식
Cl[C:2]([O:4][CH2:5][CH3:6])=[O:3].[IH:7].[CH3:8][N:9]1[CH2:13][CH2:12][N:11]=[C:10]1[NH:14][NH2:15]>N1C=CC=CC=1>[IH:7].[CH2:5]([O:4][C:2]([NH:15][NH:14][C:10]1[N:9]([CH3:8])[CH2:13][CH2:12][N:11]=1)=[O:3])[CH3:6]

참가 물질

4

반응물 2

HCID 10928Ethyl chloroformateHCID 2145886149541-82-4

생성물 1

HCID 68675322HCID 68675322, 화합물

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

Ethyl chloroformate (0.95 ml) was added dropwise to a mixture of (1-methyl-4,5-dihydro-1H-imidazol-2-yl)-hydrazine hydroiodide (CAS 49541-82-4) (2 g) and pyridine (40 ml) while stirring, and the mixture was stirred at room temperature for 2 hours. The solvent was distilled off and the residue was purified by silica gel column chromatography. The obtained compound was washed with diethyl ether to obtain the title compound (1.14 g).

후처리

  1. stirringthe mixture was stirred at room temperature for 2 hours
  2. distillationThe solvent was distilled off
  3. customthe residue was purified by silica gel column chromatography
  4. washThe obtained compound was washed with diethyl ether

출처 및 근거

ORD 기록
ord-2e0b6e814d9f4028b7332515d872a272
출처 데이터셋
uspto-grants-2012_08
특허 번호
US08252810B2

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