Allylmorpholine → N-[3-(3-Morpholin-4-yl-propyl)-5-trifluoromethyl-phenyl]-acetamide

HRID 889923

반응식

HRID 889923 반응식
[CH2:1]([N:4]1[CH2:9][CH2:8][O:7][CH2:6][CH2:5]1)[CH:2]=[CH2:3].Br[C:11]1[CH:12]=[C:13]([NH:21][C:22](=[O:24])[CH3:23])[CH:14]=[C:15]([C:17]([F:20])([F:19])[F:18])[CH:16]=1.N1(CCCC2C=C(NC(=O)C)C=C(C(F)(F)F)C=2)CCCCC1>>[N:4]1([CH2:1][CH2:2][CH2:3][C:11]2[CH:12]=[C:13]([NH:21][C:22](=[O:24])[CH3:23])[CH:14]=[C:15]([C:17]([F:18])([F:19])[F:20])[CH:16]=2)[CH2:9][CH2:8][O:7][CH2:6][CH2:5]1

참가 물질

4

반응물 3

HCID 136522AllylmorpholineHCID 21959349N-[3-bromo-5-(trifluoromethyl)phenyl]acetamideHCID 21959446N-[3-(3-Piperidin-1-yl-propyl)-5-trifluoromethyl-phenyl]-acetamide

생성물 1

HCID 21959489N-[3-(3-Morpholin-4-yl-propyl)-5-trifluoromethyl-phenyl]-acetamide

실험 절차

N-[3-(3-Morpholin-4-yl-propyl)-5-trifluoromethyl-phenyl]-acetamide was prepared from allyl morpholine and N-(3-bromo-5-trifluoromethyl-phenyl)-acetamide similar to that described in the preparation of N-[3-(3-piperidin-1-yl-propyl)-5-trifluoromethyl-phenyl]-acetamide.

출처 및 근거

ORD 기록
ord-306fc9aabcbc403fb3410bd2d3cf813c
출처 데이터셋
uspto-grants-2006_02
특허 번호
US06995162B2

연결된 노트

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