Acrylonitrile → HCID 22250584, 화합물

HRID 890247노트

반응식

HRID 890247 반응식
[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][C:8]([CH3:11])=[CH:7]2.[C:12](#[N:15])[CH:13]=[CH2:14]>O1CCOCC1>[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH2:14][CH2:13][C:12]#[N:15])[C:8]([CH3:11])=[CH:7]2

참가 물질

4

반응물 2

HCID 7855AcrylonitrileHCID 118160627-chloro-2-methyl-1H-indole

생성물 1

HCID 22250584HCID 22250584, 화합물

시약·촉매·용매 1

HCID 312751,4-Dioxane용매2회

반응 조건

온도
60 °C

실험 절차

20 g of 7-chloro-2-methyl-1H-indole are mixed in 100 ml of dioxane with 3 g of triton B, 3 g of acrylonitrile are slowly added, 250 ml of dioxane are added again and then the mixture is heated at 60° C. for 2 hours. The medium is evaporated and then the residue is taken up in AcOEt. The precipitate formed being removed, the product obtained is used as is in the following stage.

후처리

  1. additionare slowly added
  2. customThe medium is evaporated
  3. customThe precipitate formed
  4. custombeing removed
  5. customthe product obtained

출처 및 근거

ORD 기록
ord-ba29b17d0fe24ef58b35fa9cc419cc88
출처 데이터셋
uspto-grants-2006_02
특허 번호
US06995184B2

반응 노트

불러오는 중…