참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 4-Phenylcyclohexanone | HCID 78605 | — |
| 반응물 | Hydroxyamine hydrochloride | HCID 443297 | — |
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-Phenylcyclohexanone oxime | HCID 343882 | 97% |
반응 단계
A mixture of 4-phenylcyclohexanone (28.7 mmol), hydroxylamine hydrochloride (36.0 mmol), and sodium acetate (60.95 mmol) in ethanol and water was heated at 70° C. overnight. Ethanol was removed, and the residue was dissolved in water and ethyl acetate. The aqueous layer was extracted with ethyl acetate. The combined organic layers were washed with brine, dried, and concentrated to give 1-(hydroxyimino)-4-phenylcyclohexane (97%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06995269B2 |
|---|
| 출처 데이터셋 | uspto-grants-2006_02 |
|---|
| ORD ID | ord-d1c6e62fd48849e89adc22db2d64dcf8 |
|---|
| 출처 메모 | uspto-grants-2006_02 |
|---|
