N-(5-Benzyloxy-2-formylphenyl)-N-(2-hydroxypropyl)-formamide → HCID 22247174, 화합물

HRID 890896노트

반응식

HRID 890896 반응식
[CH2:1]([O:8][C:9]1[CH:16]=[CH:15][C:12]([CH:13]=[O:14])=[C:11]([N:17]([CH2:20][CH:21]([OH:23])[CH3:22])C=O)[CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>O>[CH2:1]([O:8][C:9]1[CH:16]=[CH:15][C:12]([CH:13]=[O:14])=[C:11]([NH:17][CH2:20][CH:21]([OH:23])[CH3:22])[CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

3

반응물 1

HCID 22247178N-(5-Benzyloxy-2-formylphenyl)-N-(2-hydroxypropyl)-formamide

생성물 1

HCID 22247174HCID 22247174, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Compound 3 is reacted with a base or an acid in the presence of water and an organic solvent, to yield (±)-4-benzyloxy-2-(2-hydroxypropyl)aminobenzaldehyde (6). Preferably, base is used and the preferred base is sodium hydroxide or potassium hydroxide and the preferred solvent is tetrahydrofuran and the temperature is 0 to 35° C., preferably 20 to 25° C. Preferably, an inert atmosphere, e.g., nitrogen or argon, is maintained.

출처 및 근거

ORD 기록
ord-40f214e94e6949ef9778e08dc93fc3b5
출처 데이터셋
uspto-grants-2006_02
특허 번호
US06998489B2

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