3-Ethylpentane-2,4-dione → 2-[4-(4-Ethyl-3,5-dimethyl-1H-pyrazol-1-yl)phenyl]ethanol

반응식

[CH2:1]([CH:3]([C:7](=O)[CH3:8])[C:4](=O)[CH3:5])[CH3:2].Cl.[NH:11]([C:13]1[CH:18]=[CH:17][C:16]([CH2:19][CH2:20][OH:21])=[CH:15][CH:14]=1)[NH2:12]>>[CH2:1]([C:3]1[C:7]([CH3:8])=[N:12][N:11]([C:13]2[CH:14]=[CH:15][C:16]([CH2:19][CH2:20][OH:21])=[CH:17][CH:18]=2)[C:4]=1[CH3:5])[CH3:2]

참가 물질

반응물 2

HCID 737613-Ethylpentane-2,4-dione

HCID 222447112-(4-Hydrazinophenyl)ethanol hydrochloride

생성물 1

HCID 222446192-[4-(4-Ethyl-3,5-dimethyl-1H-pyrazol-1-yl)phenyl]ethanol

실험 절차

The title compound was prepared according to the procedure described in step 1 of Example 1 from 3-ethyl-2,4-pentanedione and 2-(4-hydrazinophenyl)ethanol hydrochloride: MS (ESI) m/z 245 [M+H]+, 1H-NMR (CDCl3) δ 7.36-7.26 (4H, m), 3.84 (2H, t, J=6.6 Hz), 2.89 (2H, t, J=6.6 Hz), 2.24 (2H, q, J=7.5 Hz), 2.26 (3H, s), 2.22 (3H, s), 1.12 (3H, t, J=7.5 Hz).

출처 및 근거

ORD 기록: ord-b047a83665744c8cbae0d318ee2a944d
출처 데이터셋: uspto-grants-2006_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07001917B2

반응 노트

불러오는 중…