Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
6-Methyl-2-nitrobenzoic acid → Methyl 2-methyl-6-nitrobenzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 6-Methyl-2-nitrobenzoic acid | HCID 16097 | — |
| 반응물 | Trimethylsilyldiazomethane | HCID 167693 | — |
| 생성물 | Methyl 2-methyl-6-nitrobenzoate | HCID 596057 | — |
반응 단계
2-Methyl-6-nitrobenzoic acid is reacted with trimethylsilyldiazomethane to yield methyl 2-methyl-6-nitrobenzoate with m.p. 44–45° (Chem. Pharm. Bull., Vol. 29, 1475 (1981)). Methyl 2-methyl-6-nitrobenzoate is hydrogenated in methanol in the presence of palladium, 10% on carbon powder, at room temperature and atmospheric pressure to give methyl 2-methyl-6-aminobenzoate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07002022B2 |
| 출처 데이터셋 | uspto-grants-2006_02 |
| ORD ID | ord-c427f61a2cc74ca7982072224fa336e4 |
| 출처 메모 | uspto-grants-2006_02 |