6-Methyl-2-nitrobenzoic acid → Methyl 2-methyl-6-nitrobenzoate

HRID 891264

반응식

HRID 891264 반응식
[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([N+:11]([O-:13])=[O:12])[C:3]=1[C:4]([OH:6])=[O:5].[CH3:14][Si](C=[N+]=[N-])(C)C>>[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([N+:11]([O-:13])=[O:12])[C:3]=1[C:4]([O:6][CH3:14])=[O:5]

참가 물질

3

반응물 2

HCID 160976-Methyl-2-nitrobenzoic acidHCID 167693Trimethylsilyldiazomethane

생성물 1

HCID 596057Methyl 2-methyl-6-nitrobenzoate

실험 절차

2-Methyl-6-nitrobenzoic acid is reacted with trimethylsilyldiazomethane to yield methyl 2-methyl-6-nitrobenzoate with m.p. 44–45° (Chem. Pharm. Bull., Vol. 29, 1475 (1981)). Methyl 2-methyl-6-nitrobenzoate is hydrogenated in methanol in the presence of palladium, 10% on carbon powder, at room temperature and atmospheric pressure to give methyl 2-methyl-6-aminobenzoate.

출처 및 근거

ORD 기록
ord-c427f61a2cc74ca7982072224fa336e4
출처 데이터셋
uspto-grants-2006_02
특허 번호
US07002022B2

연결된 노트

불러오는 중…