Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-(4-Chlorophenyl)-2-furoic acid → (R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)(5-(4-chlorophenyl)furan-2-carboxamide)
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-(4-Chlorophenyl)-2-furoic acid | HCID 726693 | — |
| 반응물 | (R)-(+)-3-Aminoquinuclidine Dihydrochloride | HCID 12494972 | — |
| 생성물 | (R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)(5-(4-chlorophenyl)furan-2-carboxamide) | HCID 23599454 | — |
반응 단계
Prepared by a method analogous to that described in Example 1 from (R)-1-azabicyclo[2.2.2]oct-3-ylamine dihydrochloride and 5-(4-chlorophenyl)furoic acid; the compound was purified by chromatography on silica gel using ammoniated methanol/chloroform mixtures as the eluent; MS (ES+) 331, 333 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07001914B2 |
| 출처 데이터셋 | uspto-grants-2006_02 |
| ORD ID | ord-b26baa301631403db5127f963bca7e20 |
| 출처 메모 | uspto-grants-2006_02 |