Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5,12-Naphthacenedione → Doxorubicin
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5,12-Naphthacenedione | HCID 14160 | — |
| 반응물 | Doxorubicin Hydrochloride | HCID 443939 | — |
| 생성물 | Doxorubicin | HCID 31703 | — |
반응 단계
Doxorubicin hydrochloride, 5,12-Naphthacenedione, (8s-cis)-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-hydrochloride (hydroxydaunorubicin hydrochloride, Adriamycin) is used in a wide antineoplastic spectrum. It binds to DNA and inhibits nucleic acid synthesis, inhibits mitosis and promotes chromosomal aberrations.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07005424B2 |
| 출처 데이터셋 | uspto-grants-2006_02 |
| ORD ID | ord-d8beeddac0a94a5590148f0b1fc8a0b9 |
| 출처 메모 | uspto-grants-2006_02 |