5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine → HCID 22240203, 화합물
반응식
[CH:1]1([C:4]2[CH:5]=[C:6](B3OC(C)(C)C(C)(C)O3)[CH:7]=[C:8]([F:10])[CH:9]=2)[CH2:3][CH2:2]1.Cl[C:21]1[CH:22]=[C:23]([CH2:27][N:28]2[CH:32]=[CH:31][N:30]=[C:29]2[CH3:33])[N:24]=[N:25][CH:26]=1>>[CH:1]1([C:4]2[CH:5]=[C:6]([C:21]3[CH:22]=[C:23]([CH2:27][N:28]4[CH:32]=[CH:31][N:30]=[C:29]4[CH3:33])[N:24]=[N:25][CH:26]=3)[CH:7]=[C:8]([F:10])[CH:9]=2)[CH2:2][CH2:3]1참가 물질
3
실험 절차
The title compound was prepared from 2-(3-cyclopropyl-5-fluoro-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine. (1H-NMR (300 MHz, CDCl3) δ=9.38 (s, 1H), 6.80-7.55 (m, 6H), 5.50 (s, 2H), 2.41 (s, 3H), 1.92-2.02 (m, 1H), 1.02-1.14 (m, 2H), 0.68-0.78 (m, 2H))
출처 및 근거
- ORD 기록
- ord-59c204142b7c473988a8c9c08e323cd1
- 출처 데이터셋
- uspto-grants-2006_02