5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine → 5-(8-Fluoro-naphthalen-2-yl)-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine

HRID 891935노트

반응식

HRID 891935 반응식
[F:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[CH:10]=[C:9](B(O)O)[CH:8]=[CH:7]2.Cl[C:16]1[CH:17]=[C:18]([CH2:22][N:23]2[CH:27]=[CH:26][N:25]=[C:24]2[CH3:28])[N:19]=[N:20][CH:21]=1>>[F:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[CH:10]=[C:9]([C:16]1[CH:17]=[C:18]([CH2:22][N:23]3[CH:27]=[CH:26][N:25]=[C:24]3[CH3:28])[N:19]=[N:20][CH:21]=1)[CH:8]=[CH:7]2

참가 물질

3

반응물 2

HCID 117890255-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazineHCID 22240195(8-Fluoronaphthalen-2-yl)boronic acid

생성물 1

HCID 222402095-(8-Fluoro-naphthalen-2-yl)-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine

실험 절차

The title compound, MS: m/e=319 (M+H+), was prepared from 8-fluoro-naphthalene-2-boronic acid and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.

출처 및 근거

ORD 기록
ord-d53bcafb349a4e6ea19ea1d9f9027ee8
출처 데이터셋
uspto-grants-2006_02
특허 번호
US07005432B2

반응 노트

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