(2-Aminobenzo[d]thiazol-6-yl)methanol → 2-Aminobenzo[d]thiazole-6-carbaldehyde

HRID 892332노트

반응식

HRID 892332 반응식
[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([CH2:11][OH:12])[CH:8]=[CH:7][C:5]=2[N:6]=1>C1COCC1.[O-2].[Mn+4].[O-2]>[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([CH:11]=[O:12])[CH:8]=[CH:7][C:5]=2[N:6]=1

참가 물질

4

반응물 1

HCID 13821540(2-Aminobenzo[d]thiazol-6-yl)methanol

생성물 1

HCID 138215412-Aminobenzo[d]thiazole-6-carbaldehyde

시약·촉매·용매 2

HCID 178418406HCID 178418406, 화합물촉매HCID 8028Tetrahydrofuran용매

실험 절차

110.5 g (0.613 mol) of 1a are stirred in 200 ml of THF with 319.8 g (3.678 mol) of manganese (IV) oxide at room temperature for 3 days. The reaction mixture is filtered, the residue on the filter is washed with THF, and the filtrate is evaporated in vacuo.

후처리

  1. filtrationThe reaction mixture is filtered
  2. washthe residue on the filter is washed with THF
  3. customthe filtrate is evaporated in vacuo

출처 및 근거

ORD 기록
ord-ca63e8c4dee84989bb31bff71d484377
출처 데이터셋
uspto-grants-1992_06
특허 번호
USRE033948

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