참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Benzaldehyde | HCID 240 | — |
| 반응물 | Thiazolidinedione | HCID 5437 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 용매 | Hexane | HCID 8058 | — |
| 생성물 | 5-Benzylidene-2,4-thiazolidinedione | HCID 199154 | 109.3% |
반응 단계
Benzaldehyde (0.78 mol, 82.8 g) and 2,4-thiazolidinedione (0.85 mol, 100 g) were heated to reflux in a mixture of pyridine (215 ml) and dimethylformamide (400 ml) for 18 hours. The reaction mixture was cooled to 55° C. and diluted with hexane (360 ml) and water (900 ml) and stirred for 1 hour after cooling to room temperature. The product was collected to afford 175 g of pale yellow solid; m.p. 246°-248° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05120754 |
|---|
| 출처 데이터셋 | uspto-grants-1992_06 |
|---|
| ORD ID | ord-9d7197d11b224038a55a54a8f9b98ee7 |
|---|
| 출처 메모 | uspto-grants-1992_06 |
|---|
