Einecs 211-027-4 → 2,4-Dihydroxybenzonitrile

HRID 893028

반응식

HRID 893028 반응식
C[O:2][C:3]1[CH:10]=[C:9]([O:11]C)[CH:8]=[CH:7][C:4]=1[C:5]#[N:6].[Cl-].[NH+]1C=CC=CC=1>O>[OH:2][C:3]1[CH:10]=[C:9]([OH:11])[CH:8]=[CH:7][C:4]=1[C:5]#[N:6]

참가 물질

4

반응물 2

HCID 69401Einecs 211-027-4HCID 777502,4-Dimethoxybenzonitrile

생성물 1

HCID 30175202,4-Dihydroxybenzonitrile수율 70.6%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

2,4-dimethoxybenzonitrile (2 g) was mixed with pyridinium chloride (5.67 g) and the reaction mixture was fused at 210° C. for 2 hours. After being left to stand at room temperature overnight, the mixture was diluted with water and extracted into diethyl ether. The ether extracts were washed with water, dried over magnesium sulphate and concentrated to give a pink solid which was washed with petrol and air dried to give 2,4-dihydroxybenzonitrile (1.17 g) (m pt 176°-178° C.).

후처리

  1. waitAfter being left
  2. waitto stand at room temperature overnight
  3. extractionextracted into diethyl ether
  4. washThe ether extracts were washed with water
  5. dry with materialdried over magnesium sulphate
  6. concentrationconcentrated
  7. customto give a pink solid which
  8. washwas washed with petrol and air
  9. customdried

출처 및 근거

ORD 기록
ord-36be83b118b94df19f3b2a5413ac103c
출처 데이터셋
uspto-grants-1992_06
특허 번호
US05120869

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