Ammonium Chloride → HCID 15341843, 화합물

반응식

[CH:1]1([CH2:4][C:5]2[C:6]([OH:16])=[C:7]([CH:12]=[CH:13][C:14]=2[OH:15])[C:8](OC)=[O:9])[CH2:3][CH2:2]1.[Cl-].[NH4+:18]>>[CH:1]1([CH2:4][C:5]2[C:6]([OH:16])=[C:7]([CH:12]=[CH:13][C:14]=2[OH:15])[C:8]([NH2:18])=[O:9])[CH2:3][CH2:2]1

참가 물질

반응물 2

HCID 25517Ammonium Chloride

HCID 15341799HCID 15341799, 화합물

생성물 1

HCID 15341843HCID 15341843, 화합물

실험 절차

The compound of Example 15 is heated at 50° C. in a saturated ammonium chloride solution overnight. The reaction mixture is thoroughly extracted with ethyl acetate, and the solvent dried (Na2SO4) and evaporated in vacuo to afford the crude product. Chromatographic purification or silica gel using ethyl acetate/hexane (4:6) as eluant affords the product.

후처리

extractionThe reaction mixture is thoroughly extracted with ethyl acetate
dry with materialthe solvent dried (Na2SO4)
customevaporated in vacuo

출처 및 근거

ORD 기록: ord-71a48cbf662e413eadfd439cf6f36b22
출처 데이터셋: uspto-grants-1992_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05124350

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