Chlorotrimethylsilane → 2,5-Pyrrolidinedione, 1-(trimethylsilyl)-
반응식
[C:1]1(=[O:7])[NH:5][C:4](=[O:6])[CH2:3][CH2:2]1.C(N(CC)CC)C.[CH3:15][Si:16]([CH3:19])([CH3:18])Cl>C1(C)C=CC=CC=1>[CH3:15][Si:16]([CH3:19])([CH3:18])[N:5]1[C:4](=[O:6])[CH2:3][CH2:2][C:1]1=[O:7]참가 물질
5
실험 절차
To 400 g (4 moles) of succinimide and 900 ml of triethylamine in 2700 ml of toluene 780 ml of trimethylchlorosilane were added in two hours with vigorous stirring. After refluxing and stirring for an additional hour the mixture was allowed to cool to room temperature. The precipitate was filtered off, washed with 1 l of toluene and 1 l of light petrol (40°-60° C.) and the combined filtrate and washings concentrated to about 700 ml. N-trimethylsilylsuccinimide was isolated by distillation at diminished pressure. The yield was 573 g (3.35 moles) or 83.5%; boiling point 62° C./0.3 mm Hg.
후처리
- temperatureAfter refluxing
- filtrationThe precipitate was filtered off
- washwashed with 1 l of toluene and 1 l of light petrol (40°-60° C.)
- concentrationthe combined filtrate and washings concentrated to about 700 ml
출처 및 근거
- ORD 기록
- ord-8668dde6452545ec8d766381655a7a35
- 출처 데이터셋
- uspto-grants-1981_08
- 특허 번호
- US04282145
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