Water → HCID 18793861, 화합물

HRID 893937노트

반응식

HRID 893937 반응식
[CH2:1]([O:3][C:4](=[O:11])[CH2:5][C:6]1[N:7]=[CH:8][S:9][CH:10]=1)[CH3:2].[OH2:12]>ClCCCl>[CH2:1]([O:3][C:4](=[O:11])[C:5]([C:6]1[N:7]=[CH:8][S:9][CH:10]=1)=[O:12])[CH3:2]

참가 물질

4

반응물 2

HCID 962WaterHCID 4737345Ethyl 2-(1,3-thiazol-4-yl)acetate

생성물 1

HCID 18793861HCID 18793861, 화합물

시약·촉매·용매 1

HCID 111,2-Dichloroethane용매

실험 절차

Alternatively, the 1,3-thiazol-4-yl-glyoxyl ester is obtained by heating 17.1 g of 1,3-thiazol-4-yl-acetic acid ethyl ester in 50 ml of 1,2-dichloroethane together with 10.5 g of SeO2 with reflux on a water separator. When the separation of water is complete, the mixture is filtered with suction, the residue is washed with 1,2-dichloroethane, the combined dichloroethane phases are concentrated and the residue is distilled.

후처리

  1. customWhen the separation of water
  2. filtrationthe mixture is filtered with suction
  3. washthe residue is washed with 1,2-dichloroethane
  4. concentrationthe combined dichloroethane phases are concentrated
  5. distillationthe residue is distilled

출처 및 근거

ORD 기록
ord-b9582bed11d04d15ab86b729fd7e044e
출처 데이터셋
uspto-grants-1981_08
특허 번호
US04282220

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