Methylamine → N-Methyl-N-naphthylmethylamine

HRID 893992

반응식

HRID 893992 반응식
Cl[CH2:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]=[CH:5][CH:4]=1.[CH3:13][NH2:14]>C(O)C>[CH3:13][NH:14][CH2:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]=[CH:5][CH:4]=1

참가 물질

4

반응물 2

HCID 6329MethylamineHCID 68451-Chloromethylnaphthalene

생성물 1

HCID 84474N-Methyl-N-naphthylmethylamine

시약·촉매·용매 1

HCID 702Ethanol용매2회

실험 절차

17.6 g of 1-chloromethyl-naphthalene in 40 ml of absolute ethanol is added, dropwise, at 0° to 5°, to 100 ml of a 33% solution of methylamine in absolute ethanol. The mixture is allowed to stand overnight and is then evaporated. The residue is taken up in a little chloroform and washed with 100 ml of 1 N sodium hydroxide solution and with water. The organic phase is dried and evaporated to dryness. The residue is distilled at 0.01 Torr to obtain the heading compound as main fraction, b.p. 85°-87°.

후처리

  1. customat 0° to 5°
  2. customis then evaporated
  3. washwashed with 100 ml of 1 N sodium hydroxide solution and with water
  4. customThe organic phase is dried
  5. customevaporated to dryness
  6. distillationThe residue is distilled at 0.01 Torr
  7. customto obtain the heading compound as main fraction, b.p. 85°-87°

출처 및 근거

ORD 기록
ord-be20ca3302fa4fb6bd3a91c49836586f
출처 데이터셋
uspto-grants-1981_08
특허 번호
US04282251

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