Thionyl Chloride → HCID 57302192, 화합물

HRID 894087

반응식

HRID 894087 반응식
[C:1]([CH:9]=[CH:10][C:11]([OH:13])=O)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:16])=O>C(Cl)Cl>[C:1]([CH:9]=[CH:10][C:11]([Cl:16])=[O:13])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 94714Beta-benzoylacrylic acid

생성물 1

HCID 57302192HCID 57302192, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

3-Benzoylacrylic acid (3 g.) was refluxed for 2 hours with 100 ml. of methylene chloride and 10 ml. thionyl chloride. Concentration to dryness gave 3-benzoylacrylyl chloride. Methanol (15 ml.) was added and the resulting solution stirred for 0.5 hour. Ether (35 ml.) was added. The resulting organic mixture was washed in sequence with 15 ml. of water, 15 ml. of 1 N sodium hydroxide and twice with 15 ml. of water, concentrated to an oil, the oil triturated with 25 ml. of hot hexane, decanted from insolubles and the hexane concentrated to yield methyl 3-benzoylacrylate (1.9 g., oil, m/e 190).

후처리

  1. concentrationConcentration to dryness

출처 및 근거

ORD 기록
ord-bbaa47fa523545d9b15c202685f82276
출처 데이터셋
uspto-grants-1981_08
특허 번호
US04282242

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