Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Allyl Isothiocyanate → 3-[3-Chloro-4-hydroxy-5-(t-butyl)phenyl]-5-isothiocyanatomethyl-2-isoxazoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Allyl Isothiocyanate | HCID 5971 | — |
| 반응물 | 4-Hydroxy-3,5-bis(t-butyl)benzaldoxime | HCID 328590 | — |
| 반응물 | alpha,3-Dichloro-4-hydroxy-5-(t-butyl)benzaldoxime | HCID 136359181 | — |
| 생성물 | 3-[3-Chloro-4-hydroxy-5-(t-butyl)phenyl]-5-isothiocyanatomethyl-2-isoxazoline | HCID 135601388 | — |
반응 단계
A 25 g. portion of 4-hydroxy-3,5-bis(t-butyl)benzaldoxime was chlorinated as in Example 1 to produce 1 g. of α,3-dichloro-4-hydroxy-5-(t-butyl)benzaldoxime by chlorination and rearrangement. The intermediate was reacted with an excess of allylisothiocyanate to produce 1 g. of product, an oily liquid, NMR singlets at 1.41 and 6.18 ppm., multiplets at 2.92-3.93, 4.68-5.23 and 7.5-7.63 ppm.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04283403 |
| 출처 데이터셋 | uspto-grants-1981_08 |
| ORD ID | ord-2229091959204cb19fccf64867583496 |
| 출처 메모 | uspto-grants-1981_08 |