1,2-Dichloroethane → 4,5-Dichloro-2-(4-chlorophenoxy)anisole

HRID 894903

반응식

HRID 894903 반응식
[Cl:1]Cl.[O:3]([C:10]1[CH:15]=CC=[CH:12][C:11]=1[O:16][CH3:17])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[Cl:18][CH2:19][CH2:20][Cl:21]>>[Cl:18][C:19]1[C:20]([Cl:21])=[CH:12][C:11]([O:16][CH3:17])=[C:10]([O:3][C:4]2[CH:9]=[CH:8][C:7]([Cl:1])=[CH:6][CH:5]=2)[CH:15]=1

참가 물질

4

반응물 3

HCID 111,2-DichloroethaneHCID 24526ChlorineHCID 2487582-Methoxyphenyl phenyl ether

생성물 1

HCID 205749064,5-Dichloro-2-(4-chlorophenoxy)anisole

실험 절차

With stirring, 11.5 g of chlorine are introduced at room temperature into a solution of 8 g of 2-phenoxyanisole in 85 ml of 1,2-dichloroethane in the course of 20 minutes. The reaction mixture is then stirred for 30 minutes at room temperature. The solvent is removed by evaporation and the crystalline residue is recrystallised from methanol, affording 4,5-dichloro-2-(4-chlorophenoxy)anisole in the form of white crystals with a melting point of 105°-106° C.

후처리

  1. stirringThe reaction mixture is then stirred for 30 minutes at room temperature
  2. customThe solvent is removed by evaporation
  3. customthe crystalline residue is recrystallised from methanol

출처 및 근거

ORD 기록
ord-88182dad8232413f987ba9bd5162f0e6
출처 데이터셋
uspto-grants-1981_08
특허 번호
US04284828

연결된 노트

불러오는 중…