2-Bromonaphthalene → 2-(4-Methoxyphenyl)naphthalene

반응식

Br[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=1.[CH3:12][O:13][C:14]1[CH:19]=[CH:18][C:17]([Mg]Br)=[CH:16][CH:15]=1>>[CH3:12][O:13][C:14]1[CH:19]=[CH:18][C:17]([C:2]2[CH:11]=[CH:10][C:9]3[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=3)[CH:3]=2)=[CH:16][CH:15]=1

참가 물질

반응물 2

HCID 113722-Bromonaphthalene

HCID 178491912HCID 178491912, 화합물

생성물 1

HCID 111490142-(4-Methoxyphenyl)naphthalene

실험 절차

The title compound was prepared by reacting 2-bromonaphthalene (3.04 g, 14.7 mmol) with 4-methoxyphenylmagnesium bromide according to method used to prepared intermediate 10 to yield 2.89 g (89%) of a white solid: mp 114° C.; 1H NMR (CDCl3): δ 3.86 (3H, s), 7.01 (2H, d, J=9.06 Hz), 7.43-7.50 (2H, m), 7.65 (2H, d, J=8.73 Hz), 7.71 (1H, dd, J=1.84 Hz, J=8.56 Hz), 7.83-7.89 (3H, m), 7.98 (1H, d, J=0.67 Hz); MS (EI) m/z 234 (M)+.

출처 및 근거

ORD 기록: ord-30fed7b47b4943b9a15fee82801aeb25
출처 데이터셋: uspto-grants-2005_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06914074B2

반응 노트

불러오는 중…