2-(4-Methoxyphenyl)naphthalene → 4-(Naphthalen-2-yl)phenol

HRID 895174

반응식

HRID 895174 반응식
C[O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:18]=[CH:17][C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[CH:10]=2)=[CH:5][CH:4]=1.Cl.[NH+]1C=CC=CC=1>>[CH:10]1[C:11]2[C:16](=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:17]=[CH:18][C:9]=1[C:6]1[CH:7]=[CH:8][C:3]([OH:2])=[CH:4][CH:5]=1

참가 물질

3

반응물 2

HCID 111490142-(4-Methoxyphenyl)naphthaleneHCID 21584435Pyridinium hydrochloride

생성물 1

HCID 2368684-(Naphthalen-2-yl)phenol

실험 절차

The title compound was prepared by reacting 2-(4-methoxyphenyl)naphthalene (1.01 g, 4.31 mmol) with 10 g of pyridinium HCl at 190° C. according to method B to yield 0.84 g (89%) of a white solid: mp 148° C.; 1H NMR (DMSO-d6): δ 6.92 (2H, d, J=8.71 Hz), 7.46-7.53 (2H, m), 7.66 (2H, d, J=8.71 Hz), 7.79 (1H, dd, J=1.78 Hz, J=8.51 Hz), 7.90 (1H, d, J=8.31 Hz), 7.95 (2H, d, J=8.31 Hz), 8.11 (1H, d, J=1.19 Hz), 9.65 (1H, s); MS (ESI) m/z 219 (M−H)−.

후처리

  1. customat 190° C.

출처 및 근거

ORD 기록
ord-8e5c23ac7ebf4ebfa7aa5d69f5e17278
출처 데이터셋
uspto-grants-2005_07
특허 번호
US06914074B2

연결된 노트

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