2-Methoxy-6-phenylnaphthalene → 6-Phenylnaphthalen-2-ol

HRID 895175

반응식

HRID 895175 반응식
C[O:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[C:8]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[CH:9]=2)[CH:4]=1.Cl.[NH+]1C=CC=CC=1>>[C:13]1([C:8]2[CH:9]=[C:10]3[C:5](=[CH:6][CH:7]=2)[CH:4]=[C:3]([OH:2])[CH:12]=[CH:11]3)[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

참가 물질

3

반응물 2

HCID 112533082-Methoxy-6-phenylnaphthaleneHCID 21584435Pyridinium hydrochloride

생성물 1

HCID 101251826-Phenylnaphthalen-2-ol

실험 절차

The title compound was prepared by reacting 2-methoxy-6-phenylnaphthalene (0.54 g, 2.30 mmol) with of pyridinium HCl (10 g) at 190° C. according to method B to yield 0.32 g (63%) of a light pink solid: mp 169-170° C.; 1H NMR (DMSO-d6): δ 7.12 (1H, dd, J=2.56 Hz, J=8.54 Hz), 7.16 (1H, d, J=2.56 Hz), 7.35-7.38 (1H, m), 7.47-7.50 (2H, m), 7.73 (1H, dd, J=1.71 Hz, J=8.54 Hz), 7.76-7.79 (3H, m), 7.85 (1H, d, J=8.54 Hz), 8.08 (1H, d, J=1.28 Hz), 9.82 (1H, s); MS (ESI) m/z 219 (M−H)−.

후처리

  1. customat 190° C.

출처 및 근거

ORD 기록
ord-723f494d4d8041d483be83142a816358
출처 데이터셋
uspto-grants-2005_07
특허 번호
US06914074B2

연결된 노트

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