Diethanolamine → 4-[[Bis(2-hydroxyethyl)amino]methyl]-2,6-ditert-butylphenol

HRID 895833

반응식

HRID 895833 반응식
[C:1]([C:5]1[CH:6]=[C:7]([CH:10]=[C:11]([C:14]([CH3:17])([CH3:16])[CH3:15])[C:12]=1[OH:13])[CH2:8]Br)([CH3:4])([CH3:3])[CH3:2].[CH2:18]([NH:21][CH2:22][CH2:23][OH:24])[CH2:19][OH:20]>C1C=CC=CC=1>[C:1]([C:5]1[CH:6]=[C:7]([CH2:8][N:21]([CH2:22][CH2:23][OH:24])[CH2:18][CH2:19][OH:20])[CH:10]=[C:11]([C:14]([CH3:17])([CH3:16])[CH3:15])[C:12]=1[OH:13])([CH3:4])([CH3:3])[CH3:2]

참가 물질

4

반응물 2

HCID 8113DiethanolamineHCID 612973Phenol, 4-(bromomethyl)-2,6-bis(1,1-dimethylethyl)-

생성물 1

HCID 6129064-[[Bis(2-hydroxyethyl)amino]methyl]-2,6-ditert-butylphenol

시약·촉매·용매 1

HCID 241Benzene용매

반응 조건

온도
77.5 °C

실험 절차

In a round bottom flask taken 2.24 gm of 3,5-ditertbutyl-4-hydroxy benzyl bromide and 0.6 ml of N, N-diethanol amine and dissolved in 100 mL of benzene. The reaction mixture was refluxed with constant stirring at 75-80° C. for 6 hrs. The product was crystallized out in the form of colorless needles. The solvent was decanted, crystals were filtered off and washed with pure benzene. The yield of the product is 1.43 gm (64%). Product was identified by 1H-NMR and FT-IR spectroscopic techniques.

후처리

  1. customIn a round bottom flask taken
  2. temperatureThe reaction mixture was refluxed
  3. customThe product was crystallized out in the form of colorless needles
  4. customThe solvent was decanted
  5. filtrationcrystals were filtered off
  6. washwashed with pure benzene

출처 및 근거

ORD 기록
ord-662132d85dd44539b71e41dcfab17a69
출처 데이터셋
uspto-grants-2005_07
특허 번호
US06916960B2

연결된 노트

불러오는 중…