참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Water | HCID 962 | — |
| 반응물 | 3-(4-Methoxyphenyl)prop-2-enenitrile | HCID 34240 | — |
| 촉매 | Nickel | HCID 935 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 3-(4-Methoxyphenyl)prop-2-enal | HCID 230995 | 35% |
반응 단계
To 2 g (12.6 mmol) 4-methoxycinnamonitrile in 10:10:20 ml H2O:HOAc:pyridine was added 5 g (47 mmol) NaH2PO2 (hypophosphite) followed by 2 g RaNi. After stirring 3 hours at 50° C., the reaction mixture was filtered, extracted with CH2Cl2, washed with dilute HCl, washed with H2O and evaporated to give 0.7 g (35% yield) 4-methoxycinnamaldehyde, a yellow solid, m.p. 47° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | USRE038761E1 |
|---|
| 출처 데이터셋 | uspto-grants-2005_07 |
|---|
| ORD ID | ord-69f1bb31c39f41839482b13f761928dd |
|---|
| 출처 메모 | uspto-grants-2005_07 |
|---|
